WebInfo. BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. BindingDB supports medicinal chemistry and drug discovery via literature awareness and development of structure-activity ... http://app.drugcipher.com/

DrugCipher ...trust is good, but encryption is better!

WebShao Li. Identifying drug targets is a critical step in pharmacology. Drug phenotypic and chemical indexes are two important indicators in this field. However, in previous studies, the indexes ... WebGitHub is where people build software. More than 100 million people use GitHub to discover, fork, and contribute to over 330 million projects. date formatting ignition perspective

Performance of drugCIPHER.

WebJul 26, 2010 · We proposed a novel method, drugCIPHER, to relate pharmacological and genomic spaces, and demonstrated the good performance of this method in recovering known drug-target interactions … WebJul 25, 2010 · Principle of drugCIPHER. Drugs are solid nodes and presented by ‘ d ’; proteins are hollow nodes and presented by ‘ p ’. A ). Drug Therapeutic Similarity (TS) (blue solid edges) and Drug Chemical Similarity (CS) (green solid edges) comprise the pharmacological space. The protein-protein interaction (PPI) (gray solid edges) network ... WebFeb 12, 2013 · The drugCIPHER score refers to the likelihood of compound-target interaction calculated from the correlation between the query compound’s structure similarity vector in the drug space and the target-related gene’s functional similarity vector in the target space. The resulting target proteins with high likelihoods are considered as the ... date format thymeleaf