WebApr 13, 2024 · The safety, inherent immunogenicity, stability, and low-cost production of bacteriophages make them an ideal platform for vaccine development. Most vaccination strategies against COVID-19 have targeted the spike protein of SARS-CoV-2 to generate neutralizing antibodies. P1, a truncated RBD-derived spike protein, has been shown to … WebMar 17, 2024 · A number of factors influence immunogenicity risk including: amino acid sequence, manufacturing processes, route and frequency of administration, disease indication, co-medications, and the mechanism of action (1,2).There is a general perception that humanized and fully human mAb therapeutics are considered low-risk for …
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International Coalition of Medicines Regulatory …
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