Thioplatensimycin
WebJul 15, 2024 · Thioplatensimycin (thioPTM) and thioplatencin (thioPTN) are recently discovered thiocarboxylic acid congeners of the antibacterial compounds PTM and PTN. Here, the authors identify a thioacid ... WebThese findings explained the identification of thioplatensimycin (116) and thioplatencin (117) from the ΔptmR1 overproducer. 87 Interestingly, these compounds can also form dimeric or pseudo-dimeric structures by the nucleophilic attack of the sulfur in the thiocarboxylic acid function of one subunit to the Michael acceptor in another subunit ...
Thioplatensimycin
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WebJun 1, 2024 · Thioplatensimycin (thioPTM) and thioplatencin (thioPTN) are recently discovered thiocarboxylic acid congeners of the antibacterial compounds PTM and PTN. Here, the authors identify a thioacid ... WebAdd experiment(s): Ent-copalyl diphosphate synthase: geranylgeranyl diphosphate→(-)-ent-copalyl diphosphate (EC 5.5.1.13)No genes
WebPtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases WebBacterial lipopolysaccharide (LPS)-induced acute liver failure (ALF) is a common severe clinical syndrome in intensive care unit. No other methods are available for its prevention …
WebJan 15, 2024 · Herein, we report the detailed study of PtmC, an unusual NAT homologue encoded in the biosynthetic gene cluster for thioplatensimycin, thioplatencin, and a newly … WebOct 31, 2024 · PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases. Zheng CJ, Kalkreuter E, Fan BY, Liu YC, Dong LB, Shen B. ACS Chem Biol, 16(1):96-105, 14 Dec 2024 Cited by: 0 articles PMID: 33314918
WebJun 18, 2024 · Thioplatensimycin (thioPTM, 1) and thioplatencin (thioPTN, 2) are newly discovered thiocarboxylic acid-containing congeners of the antibacterial natural products platensimycin (PTM, 3) and ...
WebJun 18, 2024 · Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products platensimycin (PTM) and platencin (PTN), … richard aubrecht rokycanyWebJul 1, 2000 · PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases. Zheng CJ, Kalkreuter E, Fan BY, Liu YC, Dong LB, Shen … richard aubrey chaplainWebDec 13, 2024 · Headache . Upset stomach or throwing up. Diarrhea. Change in taste. These are not all of the side effects that may occur. If you have questions about side effects, call … richard aubrey fletcherWeb[ASAP] PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases. … richard aubrey of cleehongerWebJun 18, 2024 · Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products platensimycin (PTM) and platencin (PTN), were recently discovered. Here we report the biosynthetic origin of the thiocarboxylic acid moiety in thioPTM and thioPTN. We identify a thioacid cassette encoding two proteins ... richard aubryWebPtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases ACS Chemical Biology. 16(1):96-105 [DOI] 10.1021/acschembio.0c00773. redix hoursWebJun 18, 2024 · Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products platensimycin (PTM) and platencin (PTN), were recently discovered. Here we report the biosynthetic origin of the thiocarboxylic acid moiety in thioPTM and thioPTN. We identify a thioacid cassette encoding two proteins ... redi wipes dollar tree